Protocols, datasets & tools.

Published and validated protocols for iPSC reprogramming, directed differentiation, and cGMP cell manufacturing.

• Episomal iPSC reprogramming (blood/LCL)
• iEC differentiation (large-scale)
• Islet β-cell differentiation
• Motor neuron differentiation
• Bioreactor scale-up protocol

Multi-omics datasets from the NeuroLINCS and Answer ALS programs, including RNAseq, proteomics, and epigenomics.

• NeuroLINCS motor neuron transcriptomes
• Answer ALS iPSC RNA-seq (1,200+ lines)
• Endothelial cell surface proteome

Academic researchers can request access to disease-specific iPSC lines and validated antibody panels.

• ALS patient iPSC lines
• T1D patient iPSC lines
• Marfan syndrome iPSC lines
• Validated differentiation antibody panels

Computational tools developed in the lab for AI colony scoring, digital twin modeling, and multi-omics analysis.

• AI colony morphology scorer
• Bioprocess digital twin models
• NeuroLINCS multi-omics pipeline